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Year 12 in England

11th grade cells, genetics and evolution

4 11th grade cells, genetics and evolution skills, each with a worked example, free practice that checks every answer, and a printable worksheet. Start with a mixed review, or jump to the skill you need.

Mixed review

Ten questions drawn from every skill below.

Glycolysis, the Krebs cycle and the electron transport chain

CCSS NGSS.HS-LS1-7England: A level Biology: Respiration (extension)

Example

Which stage of cellular respiration: splits glucose into two pyruvate molecules?

  1. Glycolysis happens in the cytoplasm: glucose is split into two pyruvate, making a small net gain of ATP; no oxygen needed.
  2. So the answer is: glycolysis

Answer: glycolysis

Substitution, insertion and deletion mutations

CCSS NGSS.HS-LS3-2England: GCSE Biology: Inheritance, variation and evolution (mutations)

Example

Original DNA: ACT GAG GGT Mutated DNA: ACT TAG GGT What type of mutation is this?

  1. Original: 9 bases. Mutated: 9 bases.
  2. So the answer is: substitution

Answer: substitution

Selective breeding, genetic engineering and gene editing

CCSS NGSS.HS-LS3-1CCSS NGSS.HS-LS4-6CCSS NGSS.SEP 8England: GCSE Combined Science: Inheritance, variation and evolution

Example

What does CRISPR-Cas9 allow scientists to do?

  1. CRISPR uses guide RNA to direct Cas9 to a target sequence, where the DNA is cut and edited.
  2. So the answer is: cut DNA at a chosen place to edit a gene precisely

Answer: cut DNA at a chosen place to edit a gene precisely

Bases, codons and amino acids: genetic code calculations

CCSS NGSS.HS-LS1-1CCSS NGSS.HS-LS3-1England: GCSE Biology: Inheritance, variation and evolution (protein synthesis)

Example

A protein contains 141 amino acids. What is the minimum number of mRNA bases needed to code for it (ignore the stop codon)?

  1. 141 × 3 = 423
  2. So the answer is: 423

Answer: 423

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11th grade Cells, genetics and evolution: Practice and Wo...