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Science lesson plan · 9th grade (Year 10 in England) · 60 minutes

Stem cells and their medical uses

Cells, genetics and evolution

CCSS NGSS.HS-LS1-4England: GCSE Combined Science: Cell biology

Objective and success criteria

Students will: Stem cells and their medical uses.

  • I can answer questions on today's skill on my own, without help.
  • I can explain each step and say why it works.
  • I can check my answer and spot a mistake.

Before and after

Needs first: Specialised cells

Leads to: the next skill in this area.

Materials: Microscope images or slides, Cell diagrams, Mini whiteboards, A diagram or short video clip of the idea, Printed student sheet (below).

Warm-up · 6 min

  • Quick retrieval from earlier learning (Specialised cells). Students answer on mini whiteboards.
  • Show answers together and note who needs support in the main task.
  1. Which specialised cell has no chloroplasts because it is underground? (sperm cell / palisade cell / root hair cell / red blood cell) → root hair cellPrompt: What job would need this feature?
  2. What does it mean when a cell differentiates? (It becomes specialised for a particular job. / It loses all its DNA. / It dies. / It divides into four cells.) → It becomes specialised for a particular job.Prompt: Stem cells can do this.
  3. Specialised cells: which statement is true? (Sperm cells have no mitochondria. / Root hair cells contain lots of chloroplasts. / All cells in the body look the same. / Red blood cells have no nucleus.) → Red blood cells have no nucleus.Prompt: Match each cell's features to its job.

Hook · 6 min

  • Show a microscope image of cells and ask what students think they are looking at.
  • Share the objective: Stem cells and their medical uses. Read the success criteria together.

I do: model it · 12 min

  • Work through the example out loud, saying why you do each step, not just what you do.
  • Example: Where are stem cells found in a plant?
  • Step 1: Meristem tissue can differentiate into any plant cell type throughout the plant's life.
  • Step 2: So the answer is: in meristems at the tips of roots and shoots
  • Answer: in meristems at the tips of roots and shoots
  • Pause after each step and ask a student to say what comes next.

We do: guided practice · 12 min

  • Do these together. Students try each step on whiteboards before you reveal it.
  • Use the hints as prompts rather than giving the answer.
  1. What makes a stem cell different from a specialised cell? (It cannot divide / It is undifferentiated and can divide to become other cell types / It has no nucleus / It can only become a nerve cell) → It is undifferentiated and can divide to become other cell typesPrompt: "Differentiation" is when a cell becomes specialised.
  2. Stem cells: which statement is true? (Embryonic stem cells can differentiate into almost any type of human cell. / Most specialised animal cells can change into any other type of cell. / Stem cell treatments have no risks. / Adult stem cells are only found in embryos.) → Embryonic stem cells can differentiate into almost any type of human cell.Prompt: Which type of stem cell is the most flexible?

You do: independent practice · 17 min

  • Students work on the student sheet. Circulate and check the first two answers of every student early.
  • Students who finish: write a question of their own for a partner, with the answer.

The 8 questions are on the student sheet below, with answers in the key.

Exit ticket · 7 min

  • Two questions on their own. Sort answers into got it / nearly / not yet to plan the next lesson.
  1. Bone marrow transplants help some people with leukaemia (leukemia). Why? (The marrow becomes a new heart / Bone marrow contains antibiotics / Marrow cells kill all viruses / Adult stem cells in the marrow can make new healthy blood cells) → Adult stem cells in the marrow can make new healthy blood cellsPrompt: What does bone marrow normally make?
  2. Which type of stem cell: can form almost any type of human cell? (embryonic stem cells / adult stem cells / plant meristem cells) → embryonic stem cellsPrompt: Think about where each type is found.

Watch out for

  • Everyday meanings of words getting in the way of the science meaning: define key words explicitly.
  • Remembering facts without the reason: ask "why?" and "what is the evidence?"

Support and stretch

Support

  • Review first: Specialised cells.
  • Use concrete materials: microscope images or slides.
  • Give the first step of each question, or a partly worked example to finish.
  • Pair with a confident partner for the guided practice.

Stretch

  • Explain a common mistake in writing and how to fix it.
  • Write a word problem that uses today's skill, then solve a partner's.

Homework and more practice

Free online practice with hints and printable worksheets for this skill: eurekami.com/science/grade-9.

Free lesson plan from eurekami.com/lesson-plan-builder

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Stem cells and their medical uses

Name

Date

Score/ 8

  1. Question 1

    Stem cells: which statement is true?

    • A. Adult stem cells are only found in embryos.
    • B. Most specialised animal cells can change into any other type of cell.
    • C. Stem cell treatments have no risks.
    • D. Plant meristems can be used to produce clones of rare plants quickly.
  2. Question 2

    Which type of stem cell: taken from an early embryo?

    • A. embryonic stem cells
    • B. adult stem cells
    • C. plant meristem cells
  3. Question 3

    What makes a stem cell different from a specialised cell?

    • A. It has no nucleus
    • B. It cannot divide
    • C. It is undifferentiated and can divide to become other cell types
    • D. It can only become a nerve cell
  4. Question 4

    Which type of stem cell: can form almost any type of human cell?

    • A. embryonic stem cells
    • B. adult stem cells
    • C. plant meristem cells
  5. Question 5

    Where are stem cells found in a plant?

    • A. in meristems at the tips of roots and shoots
    • B. in the xylem vessels
    • C. in the leaf veins only
    • D. only in the flowers
  6. Question 6

    In therapeutic cloning, an embryo is made with the patient's own genes. What is the main advantage?

    • A. It needs no laboratory
    • B. The stem cells will not be rejected by the patient's immune system
    • C. The cells never divide
    • D. It is free of ethical questions
  7. Question 7

    Which type of stem cell: found in bone marrow?

    • A. embryonic stem cells
    • B. adult stem cells
    • C. plant meristem cells
  8. Question 8

    Which type of stem cell: used to clone rare plants quickly?

    • A. embryonic stem cells
    • B. adult stem cells
    • C. plant meristem cells

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Answer key: Stem cells and their medical uses

  1. 1. D. Plant meristems can be used to produce clones of rare plants quickly.

  2. 2. A. embryonic stem cells

  3. 3. C. It is undifferentiated and can divide to become other cell types

  4. 4. A. embryonic stem cells

  5. 5. A. in meristems at the tips of roots and shoots

  6. 6. B. The stem cells will not be rejected by the patient's immune system

  7. 7. B. adult stem cells

  8. 8. C. plant meristem cells