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Science lesson plan · 9th grade (Year 10 in England) · 45 minutes

Stem cells and their medical uses

Cells, genetics and evolution

CCSS NGSS.HS-LS1-4England: GCSE Combined Science: Cell biology

Objective and success criteria

Students will: Stem cells and their medical uses.

  • I can answer questions on today's skill on my own, without help.
  • I can explain each step and say why it works.
  • I can check my answer and spot a mistake.

Before and after

Needs first: Specialised cells

Leads to: the next skill in this area.

Materials: Microscope images or slides, Cell diagrams, Mini whiteboards, A diagram or short video clip of the idea, Printed student sheet (below).

Warm-up · 5 min

  • Quick retrieval from earlier learning (Specialised cells). Students answer on mini whiteboards.
  • Show answers together and note who needs support in the main task.
  1. Which specialised cell is a biconcave disc to carry oxygen? (red blood cell / root hair cell / sperm cell / nerve cell (neurone)) → red blood cellPrompt: What job would need this feature?
  2. What do ciliated cells in the airways do? (move mucus and trapped dirt away from the lungs / make sperm / carry oxygen in the blood / absorb food) → move mucus and trapped dirt away from the lungsPrompt: Cilia are tiny hairs that beat back and forth.
  3. Specialised cells: which statement is true? (Sperm cells have no mitochondria. / All cells in the body look the same. / Root hair cells contain lots of chloroplasts. / Stem cells can develop into many different types of cell.) → Stem cells can develop into many different types of cell.Prompt: Match each cell's features to its job.

Hook · 5 min

  • Show a microscope image of cells and ask what students think they are looking at.
  • Share the objective: Stem cells and their medical uses. Read the success criteria together.

I do: model it · 10 min

  • Work through the example out loud, saying why you do each step, not just what you do.
  • Example: Where are stem cells found in a plant?
  • Step 1: Meristem tissue can differentiate into any plant cell type throughout the plant's life.
  • Step 2: So the answer is: in meristems at the tips of roots and shoots
  • Answer: in meristems at the tips of roots and shoots
  • Pause after each step and ask a student to say what comes next.

We do: guided practice · 10 min

  • Do these together. Students try each step on whiteboards before you reveal it.
  • Use the hints as prompts rather than giving the answer.
  1. What makes a stem cell different from a specialised cell? (It cannot divide / It is undifferentiated and can divide to become other cell types / It can only become a nerve cell / It has no nucleus) → It is undifferentiated and can divide to become other cell typesPrompt: "Differentiation" is when a cell becomes specialised.
  2. Stem cells: which statement is true? (Stem cell treatments have no risks. / Adult stem cells are only found in embryos. / Embryonic stem cells can differentiate into almost any type of human cell. / Most specialised animal cells can change into any other type of cell.) → Embryonic stem cells can differentiate into almost any type of human cell.Prompt: Which type of stem cell is the most flexible?

You do: independent practice · 10 min

  • Students work on the student sheet. Circulate and check the first two answers of every student early.
  • Students who finish: write a question of their own for a partner, with the answer.

The 8 questions are on the student sheet below, with answers in the key.

Exit ticket · 5 min

  • Two questions on their own. Sort answers into got it / nearly / not yet to plan the next lesson.
  1. Which type of stem cell: used to clone rare plants quickly? (embryonic stem cells / adult stem cells / plant meristem cells) → plant meristem cellsPrompt: Think about where each type is found.
  2. Where are stem cells found in a plant? (in meristems at the tips of roots and shoots / in the leaf veins only / only in the flowers / in the xylem vessels) → in meristems at the tips of roots and shootsPrompt: Where does a plant keep growing?

Watch out for

  • Everyday meanings of words getting in the way of the science meaning: define key words explicitly.
  • Remembering facts without the reason: ask "why?" and "what is the evidence?"

Support and stretch

Support

  • Review first: Specialised cells.
  • Use concrete materials: microscope images or slides.
  • Give the first step of each question, or a partly worked example to finish.
  • Pair with a confident partner for the guided practice.

Stretch

  • Explain a common mistake in writing and how to fix it.
  • Write a word problem that uses today's skill, then solve a partner's.

Homework and more practice

Free online practice with hints and printable worksheets for this skill: eurekami.com/science/grade-9.

Free lesson plan from eurekami.com/lesson-plan-builder

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Stem cells and their medical uses

Name

Date

Score/ 8

  1. Question 1

    What makes a stem cell different from a specialised cell?

    • A. It cannot divide
    • B. It has no nucleus
    • C. It is undifferentiated and can divide to become other cell types
    • D. It can only become a nerve cell
  2. Question 2

    Stem cells: which statement is true?

    • A. Most specialised animal cells can change into any other type of cell.
    • B. Stem cell treatments have no risks.
    • C. Adult stem cells are only found in embryos.
    • D. Using embryos for research raises ethical issues that people disagree about.
  3. Question 3

    Which type of stem cell: can form blood cells but not nerve cells?

    • A. embryonic stem cells
    • B. adult stem cells
    • C. plant meristem cells
  4. Question 4

    Bone marrow transplants help some people with leukaemia (leukemia). Why?

    • A. Bone marrow contains antibiotics
    • B. The marrow becomes a new heart
    • C. Adult stem cells in the marrow can make new healthy blood cells
    • D. Marrow cells kill all viruses
  5. Question 5

    Which type of stem cell: found at root and shoot tips?

    • A. embryonic stem cells
    • B. adult stem cells
    • C. plant meristem cells
  6. Question 6

    In therapeutic cloning, an embryo is made with the patient's own genes. What is the main advantage?

    • A. It needs no laboratory
    • B. It is free of ethical questions
    • C. The stem cells will not be rejected by the patient's immune system
    • D. The cells never divide
  7. Question 7

    Which type of stem cell: taken from an early embryo?

    • A. embryonic stem cells
    • B. adult stem cells
    • C. plant meristem cells
  8. Question 8

    Which type of stem cell: can form almost any type of human cell?

    • A. embryonic stem cells
    • B. adult stem cells
    • C. plant meristem cells

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Answer key: Stem cells and their medical uses

  1. 1. C. It is undifferentiated and can divide to become other cell types

  2. 2. D. Using embryos for research raises ethical issues that people disagree about.

  3. 3. B. adult stem cells

  4. 4. C. Adult stem cells in the marrow can make new healthy blood cells

  5. 5. C. plant meristem cells

  6. 6. C. The stem cells will not be rejected by the patient's immune system

  7. 7. A. embryonic stem cells

  8. 8. A. embryonic stem cells