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Science lesson plan · 12th grade (Year 13 in England) · 30 minutes

Membrane structure, protein channels and bulk transport

Cells, genetics and evolution

CCSS NGSS.HS-LS1-2CCSS NGSS.HS-LS1-3England: A level Biology: Cell membranes (extension)

Objective and success criteria

Students will: Membrane structure, protein channels and bulk transport.

  • I can answer questions on today's skill on my own, without help.
  • I can explain each step and say why it works.
  • I can check my answer and spot a mistake.

Before and after

Needs first: Diffusion, osmosis or active transport?

Leads to: the next skill in this area.

Materials: Microscope images or slides, Cell diagrams, Mini whiteboards, A diagram or short video clip of the idea, Printed student sheet (below).

Warm-up · 4 min

  • Quick retrieval from earlier learning (Diffusion, osmosis or active transport?). Students answer on mini whiteboards.
  • Show answers together and note who needs support in the main task.
  1. Which process is this: mineral ions entering root hairs from soil with fewer ions? (diffusion / osmosis / active transport) → active transportPrompt: Is it water specifically? Is it going against the gradient?
  2. A poison stops respiration in root cells. Which process stops first? (active transport of mineral ions / osmosis of water / diffusion of oxygen / all three equally) → active transport of mineral ionsPrompt: Only one process needs energy from respiration.
  3. Transport in cells: which statement is true? (Diffusion is faster when the gradient is steeper. / Osmosis needs energy from respiration. / Water moves by osmosis from a concentrated to a dilute solution. / Active transport only happens in plants.) → Diffusion is faster when the gradient is steeper.Prompt: Which process needs energy?

Hook · 3 min

  • Show a microscope image of cells and ask what students think they are looking at.
  • Share the objective: Membrane structure, protein channels and bulk transport. Read the success criteria together.

I do: model it · 7 min

  • Work through the example out loud, saying why you do each step, not just what you do.
  • Example: Is this passive or active transport: a gland cell releasing hormone in vesicles (exocytosis)?
  • Step 1: Active transport and bulk transport use energy from ATP.
  • Step 2: So the answer is: active (uses ATP)
  • Answer: active (uses ATP)
  • Pause after each step and ask a student to say what comes next.

We do: guided practice · 6 min

  • Do these together. Students try each step on whiteboards before you reveal it.
  • Use the hints as prompts rather than giving the answer.
  1. Is this passive or active transport: simple diffusion of oxygen through the phospholipid bilayer? (passive (no ATP needed) / active (uses ATP)) → passive (no ATP needed)Prompt: Does it go down a gradient by itself?
  2. Why can oxygen cross the membrane easily but glucose needs a protein? (Glucose dissolves in fat / Glucose is a gas / Oxygen is small and non-polar; glucose is larger and polar / Oxygen is too big for proteins) → Oxygen is small and non-polar; glucose is larger and polarPrompt: The middle of the bilayer is made of fatty tails.

You do: independent practice · 7 min

  • Students work on the student sheet. Circulate and check the first two answers of every student early.
  • Students who finish: write a question of their own for a partner, with the answer.

The 6 questions are on the student sheet below, with answers in the key.

Exit ticket · 3 min

  • Two questions on their own. Sort answers into got it / nearly / not yet to plan the next lesson.
  1. Is this passive or active transport: the sodium–potassium pump? (passive (no ATP needed) / active (uses ATP)) → active (uses ATP)Prompt: Does it go down a gradient by itself?
  2. Cystic fibrosis is caused by a faulty chloride ion channel protein. What does this show? (Channel proteins carry oxygen / Ions cross membranes without help / Membrane proteins are vital for moving specific ions across membranes / Phospholipids are made of chloride) → Membrane proteins are vital for moving specific ions across membranesPrompt: Charged ions cannot pass through the fatty middle of the bilayer.

Watch out for

  • Everyday meanings of words getting in the way of the science meaning: define key words explicitly.
  • Remembering facts without the reason: ask "why?" and "what is the evidence?"

Support and stretch

Support

  • Review first: Diffusion, osmosis or active transport?.
  • Use concrete materials: microscope images or slides.
  • Give the first step of each question, or a partly worked example to finish.
  • Pair with a confident partner for the guided practice.

Stretch

  • Explain a common mistake in writing and how to fix it.
  • Write a word problem that uses today's skill, then solve a partner's.

Homework and more practice

Free online practice with hints and printable worksheets for this skill: eurekami.com/science/grade-12.

Free lesson plan from eurekami.com/lesson-plan-builder

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Membrane structure, protein channels and bulk transport

Name

Date

Score/ 6

  1. Question 1

    Membranes: which statement is true?

    • A. Large proteins pass through the membrane by simple diffusion.
    • B. The cell membrane is a phospholipid bilayer with proteins in it.
    • C. Facilitated diffusion moves substances against their gradient.
    • D. Phospholipid tails are attracted to water.
  2. Question 2

    Is this passive or active transport: a gland cell releasing hormone in vesicles (exocytosis)?

    • A. passive (no ATP needed)
    • B. active (uses ATP)
  3. Question 3

    What are the two parts of a phospholipid molecule?

    • A. two heads and no tails
    • B. a nucleus and a membrane
    • C. a protein and a sugar
    • D. a hydrophilic (water-loving) head and two hydrophobic (water-fearing) tails
  4. Question 4

    Is this passive or active transport: osmosis through aquaporin channels?

    • A. passive (no ATP needed)
    • B. active (uses ATP)
  5. Question 5

    Why can oxygen cross the membrane easily but glucose needs a protein?

    • A. Oxygen is small and non-polar; glucose is larger and polar
    • B. Oxygen is too big for proteins
    • C. Glucose dissolves in fat
    • D. Glucose is a gas
  6. Question 6

    Cystic fibrosis is caused by a faulty chloride ion channel protein. What does this show?

    • A. Membrane proteins are vital for moving specific ions across membranes
    • B. Phospholipids are made of chloride
    • C. Channel proteins carry oxygen
    • D. Ions cross membranes without help

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Answer key: Membrane structure, protein channels and bulk transport

  1. 1. B. The cell membrane is a phospholipid bilayer with proteins in it.

  2. 2. B. active (uses ATP)

  3. 3. D. a hydrophilic (water-loving) head and two hydrophobic (water-fearing) tails

  4. 4. A. passive (no ATP needed)

  5. 5. A. Oxygen is small and non-polar; glucose is larger and polar

  6. 6. A. Membrane proteins are vital for moving specific ions across membranes